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Improve Skin Conditions - Intermittent hypoxia training for treating atopic dermatitis

Modern research into atopic dermatitis is based on signs of systemic damage as a result of the pathological process following immunological, metabolic and genetic disturbances. Research (Toropova, N P Sinyavckaya J F, 1986) has shown the role of in-born, genetically mediatory enzymopathy of the digestive tract, which creates pronounced endogenous intoxication. In conditions of enzyme deficiency, dystrophy in organs and tissue will occur.

Intoxication creates hypoxia of the body. Oxygen deficiency interferes with the processes of oxidative phosphorylation, which results in the switching of aerobic metabolism to anaerobic glycolysis and a sharp reduction in the formation of an adequate quantity of adenosine triphosphate.

An energy deficit increases tissue acidosis, with consequent mitochondria damage (AZ Kolchinsaya 2001). There is a disruption to the oxidation of fatty acids, and lipids are deposited in specialised cells. The body also experiences neuroendocrine disturbance, a pathological condition of the kallikrein-kinin system, disruption of the production and mechanism of catecholomines, changes in the function and synthesis of protective anti-bodies (Skripkin Yu K, Mashkilleson, Sharapova, 1977). The deficiency of catecholomines induces the development of dystrophic cell processes. There are changes in the function of T-suppressors. These cells, which regulate the function of B-lymphocytes, inhibit the hyperproduction of IgE. A simultaneous change in the activity of T- and B-lymphocytes in patients with diffuse neurodermatitis is treated as a change in molecular, cellular, and central (immunological and neuroendocrine) levels of regulation. Stentibani (1986) hypothesises that atopy relates to the disruption of the control of the functions and metabolism of cells. According to Stentibani, it is the genetic enzymopathy of the digestive tract that conditions the complex pathological reactivity of all central life-support systems.

In the literature, there is little about the particularities of the condition of functional systems of breathing during atopic dermatitis. The present gap in presentations of the pathogenesis of atopic dermatitis should be filled. It can be assumed that the description of the condition of the functional breathing system of patients with atopic dermatitis will facilitate the working out of new methods of treating the condition. Recent scientific research in the treatment of atopic dermatitis has been aimed at discovering effective and relatively simple and safe schemes and methods. Despite significant successes in recent years, so far there have been no wholly reliable cures or long-term remissions. Current strategies have a specific range of contraindications and sometimes result in complications.

Intermittent hypoxic training is effective therapy for treating the airways and lungs, the cardio-vascular system, anaemia, chronic gynaecological and endocrine illnesses and others (T N Tsiganova, 2003). Methods of treating atopic dermatitis have been developed. It is most probable that patients with atopic dermatitis have tissue hypoxia. It is known the body’s adaptation to moderate hypoxia increases resistance to a more pronounced degree of oxygen deprivation. The adaptation to hypoxia through training should be reviewed as the most physiological method of enhancing the body’s tolerance of it (IP Ivanov, 1982). The full article can be read in BL Dermatology#9.

Possibilities for using hypoxia therapy in industrial health care for the treatment and prevention of cardiovascular diseases.

Evegnyeeba, M.V.
Materials Of the VII All-Russian Symposium on Ecological and Physiological Problems of Adaptation, p 84, 1994, Moscow

Cardiovascular disease is a significant cause of temporary and persistent inability to work. We have used adaptation to intermittent normobaric hypoxia (INH) in the prevention and treatment of this group of diseases. This consists of breathing a gas mixture consisting of 10% oxygen and 90% nitrogen.

We had under observation 56 patients (working at the Red Proletariat factory) suffering from ischemic heart disease (IHD), hypertonic (H) at the first and second stage, and neuro-circulatory dystonia (NCD).

During the course of treatment patients were given from 15 to 30 sessions of INH. At the end of the therapy the condition of 81.6% of the IHD and H patients and 72.7% of the NCD patients were found to have improved.

Lower blood pressure was noted in patients with arterial hypertension (p<0.05) and a tendency to a decrease in those observed as having normal blood pressure. data acquired from the cycling (veloergometric) test pwc showed that all patients had increased their physical performance and had increased the maximum use of oxygen by 39.6%(p<0.05). the computer program "eskiz" showed an improvement in health reserves.

In this way the results of the research provided evidence of the therapeutic and preventable efficacy of INH in patients with cardiovascular disease in an industrial environment.